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Dr Tullio Pilati
C.N.R. - Institute of Molecular Science and Technology University of Milan
Via Golgi 19, I-20133 Milan, Italy Tel: +39-02-50314245
E-mail: tullio.pilati@istm.cnr.it |
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| Senior researcher of Institute for Molecular Science and Technologies of CNR. Main research interests are the crystallographic studies of organic materials, especially hybrid perfluorocarbons-hydrocarbons materials and bioactive compounds. Also interested in the production of original crystallographic software. Access to a Bruker SMART diffractometer (see the Figure) equipped with a Bruker KRIOFLEX low temperature device and with high pressure facilities. Other two four circle diffractometers (Bruker P4 and Nonius CAD4), and various computers are available. |
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| The main research interests concern the study of free radical chemistry from both mechanistic and synthetic point of view. In the field of perfluoroalkyl radical chemistry, the attention is mainly focused in the introduction of perfluoroalkyl chains in organic molecules playing with the characteristics strong polar and enthalpic effects involved in the radical chemistry of perfluorinated radicals. |
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| The main research interests concern the development of new protocols for the synthesis of fluorinated molecules having interesting biological features. Optically active fluorinated amino acids and amino alcohols are studied as well as their incorporation in peptides and peptidomimetics. New stereocontrolled and combinatorial protocols are investigated with a particular attention on a powerful strategy for replacing the peptide bond with a very effective mimic, the trifluoroethylamine function that has recently found validation in drug discovery.
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